Table 1.
Clinical and sonographic characteristics of 38 Leydig cell tumours
| All lesions | KS-LCT | Total |
Klinefelter |
Sporadica |
|---|---|---|---|---|
| n = 38 | n = 6 | n = 32 | ||
| Number of nodules | 1 | 27 (71.1) | 3 (50.0) | 24 (75.0) |
| 2 | 5 (13.2) | 0 (0.0) | 5 (15.6) | |
| >2 | 6 (15.8) | 3 (50.0) | 3 (9.4) | |
| Echogenicity | Hypoechoic | 23 (60.5) | 3 (50.0) | 20 (62.5) |
| Faintly hypoechoic | 12 (31.6) | 1 (16.7) | 11 (34.4) | |
| Hyperechoic | 3 (7.9) | 2 (33.3) | 1 (3.1) | |
| Homogeneity | Homogeneous | 30 (78.9) | 6 (100.0) | 24 (75.0) |
| Heterogeneous | 8 (21.1) | 0 (0.0) | 8 (25.0) | |
| Size (mm) | Median (IQR) | 7.0 (4.0–11.0) | 3.0 (2.0–8.0) | 7.0 (5.0–11.5) |
| Margins | Lobulated | 19 (50.0) | 2 (33.3) | 17 (53.1) |
| Smooth | 19 (50.0) | 4 (66.7) | 15 (46.9) | |
| Vascularization | None | 2 (5.3) | 1 (16.7) | 1 (3.1) |
| Peripheral rim | 17 (44.7) | 4 (66.6) | 13 (40.7) | |
| Central | 2 (5.3) | 0 (0.0) | 2 (6.3) | |
| Mixed | 17 (44.7) | 1 (16.7) | 16 (50.0) | |
| Vascularization intensity | None | 2 (5.3) | 1 (16.7) | 1 (3.1) |
| Moderate | 18 (47.4) | 3 (50.0) | 15 (46.9) | |
| Intense | 18 (47.4) | 2 (33.3) | 16 (50.0) | |
| Adjacent pulp | Homogeneous | 29 (76.3) | 1 (16.7) | 28 (87.5) |
| Coarse | 6 (15.8) | 4 (66.7) | 2 (6.3) | |
| Multinodular | 3 (7.9) | 1 (16.7) | 2 (6.3) | |
| Microlithiasis | 4 (10.5) | 1 (16.7) | 3 (9.4) | |
| Ipsilateral testicular volume (mm3) | Median (IQR) | 8.4 (3.8–15.5) | 2.2 (1.8–3.2) | 10.1 (6.0–16.0) |
| Contralateral testicular volume (mm3) | Median (IQR) | 8.9 (4.1–11.4) | 1.4 (1.2–2.1) | 9.8 (6.1–13.0) |
| Distance from the tunica albuginea (mm) | Median (IQR) | 1.0 (1.0–3.0) | 1.3 (1.0–2.5) | 1.0 (1.0–3.3) |
KS-LCT, Leydig cell tumour found in patients with Klinfelter's syndrome; IQR, interquartile range.
All results are number of tumours (%) unless otherwise mentioned.
a
Lesions found in patients without Klinefelter syndrome.