Skip to main content
. Author manuscript; available in PMC: 2017 Jan 23.
Published in final edited form as: J Clin Exp Immunol. 2016 Oct 31;1(1):http://www.opastonline.com/wp-content/uploads/2016/11/expansion-and-productive-hiv-1-infection-of-foxp3-positive-cd4-t-cells-at-pleural-sites-of-hivtb-co-infection-jcei-16-007.pdf.

Figure 4. Expression of CCR5 and CXCR4 by Foxp3+ and Foxp3− CD4 T cells in PFMC and HIV-1 entry in PFMC.

Figure 4

Foxp3+ and Foxp3− CD4 T cells in PFMC from HIV/TB co-infected patients were assessed for expression of HIV-1 co-receptors CCR5 and CXCR4 and HIV-1 entry. A. Expression of CCR5 and CXCR4 were increased in CD4+Foxp3+ as compared to CD4+Foxp3− T cells (p < 0.01 for both, n=5). B. HIV-1 entry was assessed by PCR for HIV-1 SS DNA following immune-magnetic separation of PFMC to obtain CD4+Foxp3+ CD127− T cells and compared to that in whole PFMC. Results are shown for 2 HIV/TB co-infected patients and one HIV-1 infected subject with pleural mesothelioma.