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. Author manuscript; available in PMC: 2017 Jan 23.
Published in final edited form as: Hum Gene Ther. 2008 Mar;19(3):279–286. doi: 10.1089/hum.2007.0136

FIG. 4.

FIG. 4

Ratios of immunoreactive hEpo products in saliva and serum from mice transduced with either AdCMVhEpo-hGH or AdCMVhEpo at 1010 particles/gland. Mice were administered either vector via the submandibular glands. After 2 days serum and saliva were collected and hEpo-immunoreactive products were measured as described in Materials and Methods. Animals transduced with AdCMVhEpo-hGH had significantly higher saliva:serum ratios of immunoreactive hEpo products compared with those transduced with AdCMVhEpo (p < 0.001), that is, relatively higher levels of immunoreactive hEpo were being secreted into saliva. For these analyses, the number of mice tested was n = 32 for hEpo–hGH and n = 14 for hEpo.