Table 1.
Patient Characteristics of Patients with ALF due to BCS and a Comparison of Survivors and non-Survivors
| Characteristic | Overall | Survivors | Non-Survivors | p-value |
|---|---|---|---|---|
| Age | 38 (19–59) | 44 (26–59) | 35 (19–55) | 0.43 |
| Caucasian | 16 (84%) | 6 (75%) | 10(91%) | 0.46 |
| Female | 16 (84%) | 10 (91%) | 6 (75%) | 0.35 |
| Patients with PCV | 7 (37%) | 5(63%) | 2(18%) | 0.06 |
| Encephalopathy onset day |
2 (−1 – 19) | 6 (1–19) | 2(−1–5) | 0.07 |
| WBC (1000/mm3) | 31 (13–104) | 28.3 (13–104) | 32 (16.4 – 80.7) | 0.32 |
| Total bilirubin peak (mg/dL) |
13.8 (3.3 – 29.5) | 7.9 (5.2–29.5) | 16 (3.3–22) | 0.56 |
| AST peak (IU/L) | 3705.5 (214–11865) | 1842 (214–3811) | 5255 (1211–11856) | 0.01 |
| ALT peak (IU/L) | 2937.5 (310–6230) | 1335 (310–3400) | 4317 (708–6230) | 0.05 |
| INR peak | 5.5 (3–18.6) | 4.9 (3.1–12) | 6 (3.0–18.6) | 0.59 |
| Cr peak (mg/dL) | 3 (1.1–15.8) | 2.6 (1.07–4.8) | 4 (1.6–15.8) | 0.04 |
| MELD score | 44 (29–63) | 44.5 (29–52) | 44 (35–63) | 0.96 |
| Kings College Criteria Met |
8/17 (47%) | 3/7 (43%) | 5/11 (45%) | 0.91 |
| Anticoagulated on admission |
12/17 (71%) | 7/7 (100%) | 5/12 (42%) | 0.03 |
| Received Liver Transplant |
7 (37%) | 4 (50%) | 3 (27%) | 0.31 |
| TIPS Alone | 7 (37%) | 3 (38%) | 4 (36%) | 0.91 |
| Year of Transplant | 2005 (1999–2015) | 2010 | 2002.5 | 0.04 |
All values are either number (%) or medians (range). PCV = polycythemia vera. WBC = White blood cell. Total serum bilirubin. INR = international normalized ratio. Cr = Serum creatinine. MELD = Model for End Stage Liver Disease