Skip to main content
. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Invest Dermatol. 2016 Sep 26;137(2):350–358. doi: 10.1016/j.jid.2016.09.016

Fig. 1. CXCL9 and CXCL10 are expressed in the skin during vitiligo and form gradients within the tissue.

Fig. 1

a. REX3 mice were used as hosts in the vitiligo model as shown. b. Representative image depicting a REX3 mouse with vitiligo on the tail. c. Sample images from week 7 mice depicting chemokine clouds (10x z stack). d. Quantification of reporter expression versus depth in skin. CXCL10 is expressed more superficially than CXCL9 (3 representative mice with similar tail scores at week 7, mean ± SEM; dashed line indicates dermal-epidermal junction; 2-way ANOVA significant for depth only). e. Example of punctate CXCL10 reporter expression in a vitiligo mouse. f. Representative z stack from a naïve mouse shows very little reporter expression (10x, auto-fluorescent hairs visible; each tick on axes = 0.1mm).

HHS Vulnerability Disclosure