. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: J Am Geriatr Soc. 2016 Nov 12;65(1):35–41. doi: 10.1111/jgs.14516

Table 2.

Association Between Time-varying Warfarin, Mortality, and Thromboembolism in Adults with Atrial Fibrillation During Follow-up (Cause-specific and Subdistribution Hazards)

	No Warfarin	Warfarin
Mortality
Death events	2637	1777
Person-years	32,610.6	32,132.4
Rate	8.1/100 person-years	5.5/100 person-years
Cause-Specific Rate Ratio (Death) – unadjusted	–	0.68 (0.64–0.73)

Thromboembolism
Thromboembolism events	685	407
Person-years	32,610.6	32,132.4
Rate	2.1/100 person-years	1.3/100 person-years
Cause-Specific Rate Ratio (TE) – unadjusted	–	0.60 (0.53–0.68)
Cause-Specific Hazard Ratio (TE) – adjusted^a	–	0.57 (0.50–0.65)
Subdistribution Hazard Ratio – unadjusted	–	0.84 (0.74–0.95)
Subdistribution Hazard Ratio – adjusted^a	–	0.87 (0.77–0.99)

Adjusted for age, gender, race, prior stroke, diabetes, coronary disease, peripheral artery disease, hypertension, significant kidney dysfunction, proteinuria