Table 4.
Antimicrobial activity of extracts from barks of C. leptophloeos against selected Gram-negative bacteria and Mycobacterium.
| Commiphora leptophloeos Extract | Pseudomonas aeruginosa | Escherichia coli | Klebsiella pneumoniae | Mycobacterium smegmatis | Mycobacterium tuberculosis | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | |||
| CLMEE | 50.0 | – | 12.5 | 25 | 12.5 | – | N.d. | N.d. | N.d. | N.d. | ||
| CLCLE | 50.0 | – | 12.5 | – | 12.5 | – | 12.5 | – | 54.1 | – | ||
| CLCHE | 6.25 | – | 12.5 | – | 12.5 | 12.5 | N.d. | N.d. | N.d. | N.d. | ||
| CLAEE | – | – | 12.5 | 12.5 | 12.5 | 25 | N.d. | N.d. | N.d. | N.d. | ||
| Control | MIC | MIC | MIC | MIC | MIC | |||||||
| AMP | 0.008 | 0.004 | 0.008 | N.d. | N.d. | |||||||
| RIF | N.d. | N.d. | N.d. | 1.16 | 2.5 | |||||||
MIC, Minimal Inhibitory Concentration; MMC, Minimal Microbicidal Concentration; MIC and MMC values are expressed in mg/mL. CLAQE, C. leptophloeos aqueous extract; CLMEE, Methanolic extract; CLCLE, Cloroform extract; CLCHE, Cyclohexane extract and CLAEE, Ethyl acetate extract. AMP, Ampicillin and RIF, Rifampicin. N.d., Not determined. Data were obtained from three independent experiments, each performed in triplicates (n = 3) and represented as mean ± SD and p-value < 0.05.