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. 2017 Jan 24;7:6. doi: 10.3389/fcimb.2017.00006

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Copyright © 2017 Chambers, Aldwell, Williams, Palmer, Gowtage, Ashford, Dalley, Davé, Weyer, Salguero, Nunez, Nadian, Crawshaw, Corner and Lesellier.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Vaccination of badgers with BCG and challenged 13 weeks later with endobronchial M. bovis. Histopathology assessment. Number of sites with histological lesions (A,B), scores for granuloma severity (C,D) and collagen (E,F) in VES3 (left panel) and VES4 (right panel). Individual animal results are shown together with the group median. Badgers were vaccinated with either CB-BCG (■), HD BCG-Liporale™ (▲) or LD BCG-Liporale™ vaccine (▼). Liporale™ alone was used as a negative control for vaccination (•). A significant difference according to Dunn's test for multiple pair wise comparisons is shown by the bar.