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. 2017 Jan 24;11:4. doi: 10.3389/fncel.2017.00004

FIGURE 2.

FIGURE 2

Nocodazole treatment disrupts mitochondrial trafficking. (A) The kymographs (left) depict moving mitochondria in vehicle- (top) and nocodazole-treated (below) zebrafish larvae at 6 dpf. Right kymographs are hand-drawn traces, and the diagonal lines represent moving mitochondria (anterograde, blue lines; retrograde, pink lines). (B–E) Mitochondrial motility (B), transport direction (C; anterograde, blue; retrograde, pink), and speed (D, in the area of proximal axons; E, in the a rea of distal axons) in vehicle- (DMSO; gray) and nocodazole- (red) treated zebrafish larvae at 6 dpf. ∗∗p < 0.01, ∗∗∗p < 0.001. Error bars represent SEM.