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ORFV lesion clinical scores of sheep infected with wt and recombinant viruses. Infection with a dose of 107 p.f.u. virus of each wt, CBP knock-out virus (ko) CBP revertant virus and CBPFLAG revertant virus. There were 6 animals per group and the clinical scores are shown for each animal from day 3 to day 18 p.i. at which time the lesions in all animals had resolved (detached scab).
