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ORFV lesion clinical scores of sheep from infection with three different doses of virus (103, 105, and a 107 p.f.u.) of wt, CBP-ko, CBP-revertant and CBPFLAG- revertant at day 6 p.i. There were 6 animals per group and the clinical scores are shown for each animal. The bar represents the mean clinical score for each group and asterisks indicate where the CBP-ko virus is significantly different to wt and revertants (p < 0.05, Mann-Whitney test).
