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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Cancer. 2016 Sep 22;123(3):426–435. doi: 10.1002/cncr.30361

Table 3a. Multivariate analysis of covariates for relapse-free survival.

Parameter Hazard ratio (95% confidence interval) P value
At Response (1 – 2 months from Therapy Initiation) (N=166)

Age 1.03 (1.00, 1.07) 0.08
Cyto (Fav vs. others) 0.24 (0.07, 0.81) 0.02
Response (CRi/CRp vs. CR) 2.39 (0.92, 6.24) 0.07
MRD at CR 2.83 (1.31, 6.09) 0.008

During Consolidation (3 – 7 Months from Therapy Initiation) (N=116)

Age 1.00 (0.97, 1.04) 0.82
Cyto (Fav vs. others) 0.46 (0.15, 1.42) 0.17
Response (CRi/CRp vs. CR) 1.28 (0.39, 4.19) 0.68
MRD at 3-7 Months 50.38 (9.18, 276.63) <0.0001

At Completion of Therapy (≥ 8 Months from Therapy Initiation) (N=69)*

Age 1.00 (0.96, 1.05) 0.91
Cyto (Fav vs. others) 0.98 (0.27, 3.62) 0.98
MRD at ≥ 8 Months 12.98 (3.82, 44.12) <0.0001
*

The effect of response cannot be estimated because among the 65 evaluable patients, only 1 patient had CRp, the remaining 64 patients all had CR.