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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Cancer. 2016 Sep 22;123(3):426–435. doi: 10.1002/cncr.30361

Table 3b. Multivariate Cox regression analysis of covariates for overall survival.

Parameter Hazard ratio (95% confidence interval) P value
At Response (1 – 2 months from Therapy Initiation) (N=166)

Age 1.05 (1.00, 1.09) 0.05
Cyto (Fav vs. Others) 0.07 (0.01, 0.57) 0.01
Response (CRi/CRp vs. CR) 1.06 (0.34, 3.30) 0.93
MRD at CR 5.17 (1.98, 13.49) 0.0008

During Consolidation (3 – 7 Months from Therapy Initiation) (N=116)

Age 1.00 (0.96, 1.04) 0.89
Cyto (Fav vs. Others) 0.42 (0.09, 1.97) 0.27
Response (CRi/CRp vs. CR) 0.88 (0.22, 3.46) 0.85
MRD at 3-7 Months 12.57 (3.94, 40.07) <0.0001

At Completion of Therapy (≥ 8 Months from Therapy Initiation) (N=69)*

Age 1.01 (0.97, 1.06) 0.60
Cyto (Fav vs. Others) 0.91 (0.14, 5.75) 0.92
MRD at ≥ 8 Months 10.19 (2.34, 44.34) 0.002
*

The effect of response cannot be estimated because among the 65 evaluable patients, only 1 patient had CRp, the remaining 64 patients all had CR.