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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Am Geriatr Soc. 2016 Nov 29;65(1):51–58. doi: 10.1111/jgs.14549

Table 2.

Longitudinal analysis of association of recent readmission and cumulative readmissions with changes in physical functioning (N=566) to 18 months post-hospitalization.

aAcute and Longer-term Associations Estimated Separately bAcute and Longer-term Associations Estimated Simultaneously
SAGES Physical Function Composite Mean Difference
(95% CI)
Mean Difference
(95% CI)
Hospitalized since last study visit −2.8
(−3.8, −1.8)
−1.4
(−2.5, −0.2)
Cumulative readmissions to date
  0 Referent Referent
  1 −2.1
(−3.2, −1.004)
−1.5
(−2.6, −0.4)
  2+ −4.7
(−6.2, −3.3)
−4.0
(−5.6, −2.4)

Instrumental Activities of Daily Living; one or more dependencies cRelative Risk
(95% CI)
Relative Risk
(95% CI)
dHospitalized since last study visit 1.5
(1.4, 1.7)
1.2
(0.99, 1.4)
Cumulative readmissions to date
  0 Referent Referent
  1 1.5
(1.3, 1.8)
1.4
(1.2, 1.7)
  2+ 2.0
(1.7, 2.5)
1.8
(1.5, 2.3)

Activities of Daily Living; one or more dependencies Relative Risk
(95%CI)
Relative Risk
(95%CI)
Hospitalized since last study visit 2.1
(1.4, 3.0)
1.3
(0.9, 2.0)
Cumulative readmissions to date
  0 Referent Referent
  1 1.9
(1.3, 2.8)
1.6
(1.0, 2.5)
  2+ 4.1
(2.3, 7.2)
3.3
(1.7, 6.4)

MOS SF-12 Physical Component Summary Mean Difference
(95% CI)
Mean Difference
(95% CI)
Hospitalized since last study visit −2.3
(−3.2, −1.4)
−1.5
(−2.6, −0.4)
Cumulative readmissions to date
  0 Referent Referent
  1 −1.2
(−2.2, −0.3)
−0.7
(−1.7, 0.4)
  2+ −3.3
(−4.6, −1.9)
−2.4
(−4.0, −0.9)

Analyses based on 503 hospital readmissions. MOS SF-12 – Medical Outcomes Study Short Form-12; CI – Confidence Interval. Models adjust for participants’ baseline age, sex, race/ethnicity, years of education, body mass index, Charlson comorbidity index, and surgery type. The time trend is allowed to vary freely in a nonlinear fashion from baseline through the 1 and 2 month visits, and assumed to follow a linear course thereafter, consistent with exploratory analyses (Figure 1).

a

Recent hospitalization and cumulative history of hospitalization considered in separate models

b

Recent hospitalization and cumulative history of hospitalization considered in one combined model (i.e. controlling for one another)

c

Multiplicative increase in the probability of ADL or IADL dependency vis-à-vis referent category

d

Referent: no hospitalization at current visit