Table 3.
Multivariable models for marginally significant associations of scaled dietary foods and nutrients with cortical thickness in regions of interest
| Model * | |||||
|---|---|---|---|---|---|
| Dietary measures | Cortical thickness | Beta | 95% CI | P | |
| Positive associations | |||||
| Vegetables | Middle temporal | .010 | −.001, | .020 | .07 |
| Linolenic | Middle temporal | .010 | −.001, | .020 | .08 |
| B carotene | Lingual | .007 | −.001, | .015 | .09 |
| Middle temporal | .009 | −.002, | .019 | .10 | |
| Superior frontal | .011 | −.000, | .022 | .06 | |
| Superior parietal | .010 | −.000, | .021 | .06 | |
| Orbitofrontal | .008 | −.002, | .018 | .10 | |
| Vitamin C | Temporal pole | .018 | −.003, | .039 | .09 |
| Negative associations | |||||
| % sugar | Precuneus | −.010 | −.019, | .000 | .05 |
| Parietal | −.008 | −.017, | .001 | .08 | |
| Composite lobar | −.007 | −.014, | .001 | .07 | |
| AD signature | −.010 | −.020, | .001 | .07 | |
| % saturated fat | Lingual | −.007 | −.016, | .001 | .09 |
| Middle temporal | −.010 | −.021, | .001 | .07 | |
| % total fat | Inferior temporal | −.011 | −.022, | .001 | .06 |
MUFA/SFA, monounsaturated fat/saturated fat ratio. BMI, body mass index, Dietary measures are log or square root transformed where necessary, and standardized.
Estimates for association of MeDi components with imaging measures were .05 ≤ P ≤ .1. The model is adjusted for age, sex, education, total energy intakes, BMI, diabetes, hypertension, coronary heart disease, peripheral vascular disease, congestive heart failure, atrial fibrillation, dyslipidemia, stroke, and depressive symptoms.