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. Author manuscript; available in PMC: 2017 Jan 24.
Published in final edited form as: Biol Blood Marrow Transplant. 2014 Apr 24;20(9):1307–1313. doi: 10.1016/j.bbmt.2014.04.018

Figure 2. Comparison of molecular MRD sensitivity in bone marrow aspirates and peripheral blood.

Figure 2

In 37 paired bone marrow (BM) aspirate and peripheral blood (PB) samples, MRD quantification was concordantly negative (0) in 18 (49%). MRD quantification was discordantly positive in BM while negative in PB in 4 (11%), and the median disease burden in these BM samples was 5.5×10−6 (range 4.5×10−6 – 1.7×10−5). When MRD was detected in both sample sources, disease burden was higher (median 8.4-fold) in BM than PB (A). MRD quantification in all samples in this study is demonstrated (B).