Table 1.
Creatinine and urea plasma levels, urine volume, and urine to plasma osmolality ratio (U/P) in Sham, BUO-1, BUO-2, and BUO-7 rats.
| Sham (n = 16) |
BUO-1 (n = 5) |
BUO-2 (n = 6) |
BUO-7 (n = 5) |
|
|---|---|---|---|---|
| Plasma creatinine (mg/dL) | 0.35 ± 0.03 | 1.40 ± 0.20a,c,d | 0.97 ± 0.12a,b,d | 0.51 ± 0.06b,c |
| Plasma urea (g/L) | 0.56 ± 0.09 | 2.91 ± 0.67a,c,d | 1.78 ± 0.61a,b,d | 0.60 ± 0.09b,c |
| Urine volume (μL/min/100 g b.w) | 5.01 ± 0.74 | 11.60 ± 1.12a,c,d | 7.95 ± 1.17b | 5.23 ± 0.52b |
| U/P | 4.19 ± 0.41 | 1.83 ± 0.21a,d | 2.10 ± 0.17a,d | 3.79 ± 0.25b,c |
Results are expressed as means ± SE. BUO: bilateral ureteral obstruction; BUO-1: 1 day after releasing of BUO; BUO-2: 2 days after releasing of BUO; BUO-7: 7 days after releasing of BUO; sham: sham-operated rats. Statistical comparison between experimental groups was made by one-way ANOVA plus Newman-Keuls. aP < 0.05 versus sham, bP < 0.05 versus BUO-1, cP < 0.05 versus BUO-2, and dP < 0.05 versus BUO-7.