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β-Catenin is a target of miR-200a, and miR-200a represses β-catenin expression in HCT116 cells. (a) miR-200a reduces the luciferase activity of a WT β-catenin reporter plasmid, as demonstrated via a luciferase reporter assay (P < 0.01). (b) miR-200a overexpression decreases β-catenin levels, as demonstrated via western blot analysis. “∗∗” refers to P < 0.01.
