Table 2.
Comparison of demographic, clinical, and respiratory cytology findings at presentation in dogs with less severe bacterial pneumonia (BP) (requiring <2 days of hospitalization, n = 10) and more severe BP (requiring >2 days of hospitalization, n = 9, including 2 mortalities)
| Dogs with <2 Days of Hospitalization Mean ± SD or Median (IQR) | Dogs with >2 Days Hospitalization Mean ± SD or Median (IQR) | P‐Value | |
|---|---|---|---|
| Duration of hospitalization (days) | 1.0 (0.5–1.1) | 5.5 (3.3–5.8) | |
| Age (years) | 1.5 (0.8–5.6) | 5.8 (2.6–7.6) | .211 |
| Sex |
Male 6/10 Female 4/10 |
Male 5/9 Female 4/9 |
|
| Duration of clinical signs (days) | 3.0 (1.0–7.0) | 1.5 (1.0–3.5) | .315 |
| Body weight (kg) | 36.5 ± 17.5 | 33.6 ± 24.6 | .764 |
| Body temperature (°C) | 39.3 ± 0.9 | 39.6 ± 0.9 | .419 |
| Respiratory rate (breaths/min) | 43 ± 22 | 61 ± 17 | .064 |
| Blood hematology (n = 19) | |||
| Leukocyte count (109/L) | 20.2 ± 16.3 | 12.1 ± 6.5 | .183 |
| Segmented neutrophil count (109/L) | 15.9 ± 14.2 | 9.3 ± 5.5 | .234 |
| Band neutrophil count (109/L) | 0.1 (0.0–0.7) | 1.4 (0.3–2.8) | .035 |
| Lymphocyte count (109/L) | 2.2 ± 1.6 | 0.5 ± 0.3 | .009 |
| Eosinophil count (109/L) | 0.4 ± 0.4 | 0.1 ± 0.2 | .078 |
| Monocyte count (109/L) | 0.7 (0.4–2.3) | 0.4 (0.2–1.4) | .278 |
| Basophil count (109/L) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | .720 |
| Arterial blood gas analysis (n = 19) | |||
| Arterial Pao 2 (mmHg) | 84.6 ± 6.8 | 69.0 ± 9.8 | .001 |
| Arterial Paco 2 (mmHg) | 30.8 (27.0–31.1) | 28.8 (28.4–32.2) | .842 |
| Alveolar–arterial O2 gradient | 30.8 ± 10.8 | 46.5 ± 9.2 | .003 |
| pH | 7.41 ± 0.02 | 7.41 ± 0.6 | .893 |
| HCO3 (mmol/L) | 18.2 ± 1.7 | 18.7 ± 3.4 | .669 |
| Base excess (mEq/L) | −4.6 ± 1.3 | −4.3 ± 3.9 | .833 |
| Respiratory sample cytology (n = 15) | |||
| Neutrophils (%) | 14.7 (5.3–76.2) | 96.4 (46.8–97.8) | .019 |
| Eosinophils (%) | 3.7 (0.6–13.2) | 0.0 (0.0–0.4) | .008 |
| Mast cells (%) | 0.0 (0.0–2.7) | 0.0 (0.0–0.0) | .254 |
| Lymphocytes (%) | 14.6 ± 11.2 | 2.3 ± 3.1 | .008 |
| Macrophages (%) | 42.9 ± 22.9 | 17.2 ± 27.6 | .077 |
| Epithelial cells (%) | 0.0 (0.0–0.2) | 0.0 (0.0–8.5) | 1.000 |
SD, standard deviation; IQR, interquartile range.