Figure 10.

Effects of fenofibrate treatment on high-fat-diet-induced inflammation and apoptosis. (a) Liver cleaved caspase-1 (n = 4), (b) liver IL1ββ (n = 4), (c) liver BCL2/BAX ratio (n = 7–9), (d) liver cleaved caspase-3 (n = 6) and number of apoptotic cells (TUNEL-positive cells), and (c) representative images and (d) quantification (n = 3) from NTg and apoCIII mice fed either a low-fat (LF) or high-fat (HF) diets for 16 weeks. Data are expressed as the mean ± SEM. ^$LF versus HF group; ^#NTg versus apoCIII mice (p < 0.05; two-way ANOVA). ^{A, B}Mean values with nonmatching superscript letters are significantly different (p < 0.05; ANOVA followed by Bonferroni correction).