Figure 9.
Effects of apoCIII overexpression and high-fat diet consumption on liver cell death. (a) Ratio between the anti- and proapoptotic proteins BCL2 and BAX (n = 7–9), (b) cleaved (activated) caspase-3 (n = 5-6) and number of apoptotic cells (TUNEL-positive cells), and (c) representative images and (d) quantification (n = 3) in NTg and apoCIII mice fed either a low-fat (LF) or high-fat (HF) diets for 16 weeks. Data are expressed as the mean ± SEM. ∗LF versus HF group; #NTg versus apoCIII mice (p < 0.05; two-way ANOVA). A, B, ABMean values with nonmatching superscript letters are significantly different (p < 0.05; ANOVA followed by Bonferroni correction).