Figure 2. At 2 weeks after a full transverse crush SCI, Foxj1-tdT expressing cells have not migrated into lesions and remain primarily near the ependymal layer.

(a) Schematic of crush SCI and 5 dorso-ventral levels of horizontal sections used for qualitative and quantitative analyses. (b,c) Schematics of horizontal views of middle level (M) and dorsal (D) or ventral (V) levels showing ependyma (Ep) as well as demarcations of astrocyte scar (AS) and lesion core (LC) used for analyses. (c–f) Single channel and merged immunofluorescence images showing distribution of Foxj1-tdT positive ependymal cells and their progeny in relation to the LC and to GFAP positive astrocytes in the AS.