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. 2017 Jan 24;7:41143. doi: 10.1038/srep41143

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The correlation between DAS28 and the plasma IL-22 level (A), the plasma level of IL-17 level (B), the percentage of circulating Th22 cells (C), the percentage of circulating IL-22⁺Th1 cells (D), or the percentage of circulating IL-22⁺Th17 cells (E) in untreated RA; the correlation between the decrease of DAS28 and the decrease of the plasma level of IL-22 (F) in RA responders after treatment; the correlation between the DAS28 and the plasma level of IL-22 (G), the percentage of circulating Th22 cells (H) in RA non-responders after treatment were analyzed using Spearman’s rank correlation test.