Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 24;7:41167. doi: 10.1038/srep41167

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Panel (A) Michaelis-Menten curves of ¹⁴C urate kinetics of hSLC2A9 WT (▪), Y298Q (○) and N429H (Δ). Panel (B) ¹⁴C urate kinetic constants and the standard error of the regression (Sy. X) of the three isoforms (n ≥ 3). Panel (C) Michaelis-Menten curves of urate-induced currents of WT hSLC2A9, Y298Q and N429H mutants. Panel (D) Urate-induced current kinetic constants and the standard error of the regression (Sy. X) of the WT and two mutants (n ≥ 15 oocytes from 3 frogs). Panel (E) Current-voltage curve of 1 mM urate-induced current obtained using a RAMP protocol WT hSLC2A9 (▪), Y298Q (○) and N429H (Δ) mutant expressing oocytes. (n ≥ 15 oocytes from 3 frogs). Panel (F) ¹⁴C fructose uptake mediated by WT hSLC2A9 and its mutants. (n ≥ 3, One-way ANOVA, *p < 0.05).