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. Author manuscript; available in PMC: 2017 Jan 24.
Published in final edited form as: Brain Struct Funct. 2015 Feb 7;221(3):1681–1689. doi: 10.1007/s00429-015-0997-8

Figure 3. Optical inhibition of PL-to-NAcore projection prevents synaptic potentiation.

Figure 3

A) Increase in AMPA/NMDA after cue-induced reinstatement was blocked by 15 min optogenetic inhibition of PL terminals in the NAcore. Data shown as mean ± SEM ratio for each treatment group, with individual cells indicated in smaller circles. N refers to number of animals. Representative traces are shown for each treatment in the left panel. B) sEPSC amplitude was increased in the sham but not the laser group, supporting a postsynaptic potentiation mechanism. C) sEPSC frequency was not different between groups.

*p< 0.05, comparing reinstated sham to the other groups.