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. 2017 Jan 24;7:41105. doi: 10.1038/srep41105

Figure 3. Sensitivity of CpomORs to amiloride derivatives when expressed in HEK293T cells.

Figure 3

Amiloride derivative, MIA, 100 μM, applied extracellularly completely blocked the VUAA3 activated calcium signal. Similar results were observed for both homomeric (top-left panel) and all heteromeric complexes. Note: the effects were only partially reversible.