Figure 2. Microarray validation of gene array of SHP regulated genes using the RT² Profiler™ PCR Array.

(A,B) Scatter plot and clustergram of microarray data showing DEGs that are regulated by SHP (positively in red, negatively in green) in HSC-T6 stimulated with CDCA (A) or HSC-T6 overexpressing SHP (B). (C) Effect of CDCA treatment (white bars) and SHP over-expression (black bars) on the relative mRNA expression of CXCL12, TGFBR2, DAG1 GR, NCoR1 and Rb1.