Table 4. Univariate analysis of factors in patients with baseline PET/CT (n = 47).
| Risk Factor | PFS |
OS |
||||
|---|---|---|---|---|---|---|
| Mean (SE) | 95% CI | P | Mean (SE) | 95% CI | P | |
| Sex | ||||||
| Male | 27.70 (4.36) | 19.15–36.25 | 0.181 | 38.66 (3.62) | 31.56–45.75 | 0.706 |
| Female | 40.06 (5.05) | 30.16–49.97 | 44.81 (4.47) | 36.05–53.57 | ||
| Age | ||||||
| Age ≤ 60 | 34.42 (3.81) | 26.97–41.88 | 0.813 | — | — | 0.243 |
| Age > 60 | 28.25 (10.87) | 6.93–49.67 | — | — | ||
| B symptoms | ||||||
| No | 41.03 (4.76) | 31.69–50.36 | 0.085 | 48.17 (3.63) | 41.06–55.28 | 0.150 |
| Yes | 26.20 (4.41) | 17.56–34.85 | 35.44 (3.84) | 27.91–42.97 | ||
| ECOG | ||||||
| <2 | 31.85 (3.84) | 24.34–39.37 | 0.776 | 40.28 (3.18) | 34.05–46.51 | 0.673 |
| ≥2 | 32.77 (6.67) | 19.69–45.85 | 41.39 (5.67) | 30.28–52.49 | ||
| LDH level | ||||||
| ≤245 U/L | 33.80 (4.23) | 25.50–42.09 | 0.386 | 41.40 (3.39) | 34.75–48.04 | 0.515 |
| >245 U/L | 31.50 (5.36) | 21.00–41.99 | 41.09 (4.70) | 31.88–50.31 | ||
| IPI score | ||||||
| 0–1 | 32.24 (3.79) | 24.82–39.66 | 0.782 | 40.34 (3.17) | 34.13–46.55 | 0.706 |
| 2–5 | 33.15 (6.57) | 20.27–46.03 | 41.46 (5.66) | 30.38–52.55 | ||
| KPI score | ||||||
| 0–2 | 39.09 (4.10) | 31.05–47.13 | 0.036 | 48.44 (3.02) | 42.53–54.35 | 0.015 |
| 3–4 | 16.33 (3.15) | 10.17–22.50 | 21.54 (2.65) | 16.36–26.73 | ||
| Ann Arbor Stage | ||||||
| I/II | 30.90 (3.55) | 23.94–37.86 | 0.603 | 40.21 (2.64) | 35.04–45.38 | 0.072 |
| III/IV | 32.65 (5.79) | 21.31–43.99 | 36.71 (5.31) | 26.30–47.12 | ||
| Baseline SUVmax | ||||||
| ≤15.1 | 39.10 (4.57) | 30.15–48.05 | 0.097 | 50.99 (2.69) | 45.72–56.25 | 0.005 |
| >15.1 | 26.50 (4.63) | 16.99–36.02 | 31.91 (4.47) | 23.14–40.67 | ||
| Baseline WBMTV | ||||||
| ≤16.1 | 43.43 (3.79) | 36.01–50.86 | 0.000 | 48.38 (3.05) | 42.40–54.35 | 0.018 |
| >16.1 | 17.50 (4.60) | 8.48–26.52 | 30.71 (5.06) | 20.80–40.63 | ||
| Baseline WBTLG | ||||||
| ≤44.7 | 49.93 (3.34) | 43.38–56.48 | 0.000 | 52.47 (2.45) | 47.67–57.26 | 0.012 |
| >44.7 | 20.42 (4.02) | 12.55–28.30 | 33.53 (3.78) | 26.13–40.94 | ||
ECOG, Eastern Cooperative Oncology Group; IPI, International Prognostic Index; KPI, Korean prognostic index; SUVmax, maximum standardized uptake value; WBMTV, whole-body metabolic tumour volume; WBTLG, whole-body total lesion glycolysis; PFS, progression-free survival; OS, overall survival.