. Author manuscript; available in PMC: 2017 Jan 24.

Published in final edited form as: Biochemistry. 2015 Sep 17;54(38):5828–5838. doi: 10.1021/acs.biochem.5b00828

Table 1. $S_{axis}^{2}$ values for various residue types in ϕ12 P2.

Domain	Residue	Apo	Mg²⁺	Mg²⁺/GMPCPP	ts-mutant
Fingers	Ile	0.63±0.27 (10)	0.67±0.32 (10)	0.61±0.27 (10)	0.66±0.28 (10)
	Leu	0.69±0.30 (22)	0.74±0.29 (22)	0.69±0.29 (21)	0.73±0.32 (21)
	Val	0.71±0.32 (20)	0.74±0.33 (22)	0.66±0.32 (19)	0.79±0.31 (21)
	Met	0.31±0.18 (6)	0.38±0.23 (7)	0.36±0.23 (7)	0.33±0.17 (6)
	Total	58	61	57	58
Thumb	Ile	0.72±0.20 (7)	0.72±0.18 (7)	0.68±0.20 (6)	0.76±0.21 (7)
	Leu	0.55±0.24 (11)	0.59±0.29 (11)	0.55±0.26 (11)	0.55±0.31 (12)
	Val	0.87±0.12 (9)	0.93±0.16 (11)	0.84±0.13 (9)	0.97±0.22 (9)
	Met	0.48 (1)	0.60 (1)	None	None
	Total	28	30	26	28
Palm	Ile	0.87±0.12 (6)	0.93±0.08 (6)	0.82±0.07 (6)	0.84±0.27 (7)
	Leu	0.55±0.29 (15)	0.63±0.26 (14)	0.57±0.27 (15)	0.59±0.28 (14)
	Val	0.75±0.29 (11)	0.82±0.31 (14)	0.75±0.28 (15)	0.77±0.32 (12)
	Met	0.43±0.18 (4)	0.44±0.18 (5)	0.45±0.17 (5)	0.45±0.18 (5)
	Total	36	39	41	38
CTD	Ile	0.57±0.43 (2)	0.70±0.57 (2)	0.54±0.39 (2)	0.71±0.59 (2)
	Leu	None	0.78±0.09 (2)	0.74±0.03 (2)	None
	Val	0.50±0.38 (3)	0.61±0.36 (4)	0.50±0.36 (3)	0.51±0.36 (4)
	Met	0.43 (1)	0.58±0.12 (2)	0.54±0.12 (2)	0.65±0.19 (2)
	Total	6	10	9	8
Overall^a	Ile	0.71±0.24 (26)	0.75±0.26 (26)	0.68±0.22 (25)	0.74±0.27 (27)
	Leu	0.60±0.29 (51)	0.67±0.28 (51)	0.61±0.27 (52)	0.63±0.31 (50)
	Val	0.72±0.30 (45)	0.78±0.31 (53)	0.70±0.29 (48)	0.78±0.32 (47)
	Met	0.37±0.17 (12)	0.44±0.20 (15)	0.42±0.19 (14)	0.42±0.20 (13)
	Total	134	145	139	137

Total for all Ile, Leu, Val and Met residues including those that do not belong to the canonical domains. Average values and the corresponding standard deviations are calculated over all residues of a particular type in a given structural domain.

Table 1. Saxis2 values for various residue types in ϕ12 P2.

Table 1. $S_{axis}^{2}$ values for various residue types in ϕ12 P2.