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. 2017 Jan 23;17:94. doi: 10.1186/s12879-017-2205-3

Table 1.

Assessing macroscopic hepatic lesions in CD1 mice

Group Treatment Lesion score (mean ± SEM) Reduction (%)
1 Untreated uninfected
2 Infected 12.0 ± 1.5
3 Adjuvant treated 9.3 ± 1.8 22
4 B6 + T14 8.3 ± 1.8 31
5 B1 + B5 + B6 10.3 ± 1.6 14
6 T14 + T15 + T16 6.6 ± 0.6 45*
7 B1 + B2 + B5 + B6 + T14 + T15 + T16 7.3 ± 1.3 39*

The mice were immunised with combinations of synthetic peptides containing B- and T-cell epitopes using the ADAD vaccination system which had been orally challenged with 7 F. hepatica metacercariae

*p < 0.05 compared to infected controls