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. 2017 Jan 23;17:71. doi: 10.1186/s12906-016-1554-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of K36E on α-MSH-induced expression of tyrosinase in B16F0 cells after treatment with H-89. (Significant difference vs. control: ###, P < 0.001; significant difference vs. α-MSH-treated group: **, P < 0.01; ***, P < 0.001)