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. 2017 Jan 23;10:29. doi: 10.1186/s13045-017-0400-8

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of blocking DOT1L in the cell apoptosis and cell cycle. After exposure to 10 μM EPZ004777 and SGC0946 seperately for 12 days in both SK-OV-3 and TOV21G cells, cell apoptosis and cell cycle analyses in each group were determined by flow cytometry. a The typical images and b the proportion of apoptosis cell were measured in SK-OV-3 and TOV21G cells. The proportion of cell cycle distribution in SK-OV-3 cells (c) and in TOV21G cells (d) was shown. Columns are the mean of triplicate samples