Table 2.

Survival analysis by univariate and multivariate methods to identify prognostic factors in HCC

	Univariate analysis			Multivariate analysis
	HR	p value	95% CI	HR	p value	95% CI
SESN2 expression
High versus Low	0.271	0.001*	0.136–0.542	0.308	0.003*	0.140–0.678
Gender
Male versus Female	1.140	0.732	0.539–2.414
Age (years)
< 60 versus ≥60	1.630	0.084	0.937–2.838
Hepatitis B virus infection
Positive versus Negative	1.111	0.900	0.526–1.539
Hepatitis C virus infection
Positive versus Negative	1.799	0.036*	1.039–3.114	0.940	0.851	0.493–1.793
Liver cirrhosis
Positive versus Negative	1.137	0.644	0.660–1.959
Tumour size (cm)
> 5 versus ≤5	1.412	0.219	0.814–2.449
Lymph node metastasis
Positive versus Negative	2.795	0.001*	1.621–4.821	1.839	0.063	0.968–3.495
Distant metastasis
Positive versus Negative	2.709	0.003*	1.417–5.179	0.925	0.846	0.421–2.033
TNM stage
Stage I-II versus Stage III-IV	0.276	0.001*	0.144–0.527	0.352	0.003*	0.178–0.696

*p < 0.05