TABLE 4.
n | Any Fail | Fine Motor | Gross Motor | Communication | Personal-Social | Problem Solving | |
---|---|---|---|---|---|---|---|
Primary cohort | |||||||
1 (maternal <25 and paternal <25) | 776 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
2 (maternal 25–35 and paternal <25) | 444 | 1.18 (0.77–1.81) | 2.38 (1.26–4.49)a | 0.86 (0.41–1.81) | 1.14 (0.57–2.27) | 1.51 (0.78–2.92) | 1.25 (0.61–2.56) |
3 (maternal 35+ and paternal <25) | 99 | 1.38 (0.61–3.14) | 1.48 (0.48–4.60) | 1.29 (0.29–5.85) | 1.70 (0.42–6.91) | 1.16 (0.29–4.62) | 1.63 (0.43–6.12) |
4 (maternal <25 and paternal 25–35) | 1421 | 1.01 (0.72–1.42) | 1.16 (0.68–2.01) | 0.75 (0.42–1.35) | 0.78 (0.44–1.40) | 1.45 (0.83–2.53) | 1.10 (0.60–2.02) |
5 (maternal 25–35 and paternal 25–35) | 1199 | 1.02 (0.72–1.43) | 1.25 (0.73–2.15) | 0.70 (0.39–1.26) | 1.13 (0.65–1.97) | 1.55 (0.91–2.66) | 1.32 (0.74–2.37) |
6 (maternal 35+ and paternal 25–35) | 369 | 1.06 (0.64–1.73) | 1.52 (0.70–3.26) | 0.73 (0.29–1.83) | 1.20 (0.54–2.67) | 2.32 (1.16–4.64)a | 1.70 (0.76–3.82) |
7 (maternal <25 and paternal 35+) | 117 | 1.23 (0.56–2.72) | 0.97 (0.26–3.57) | 0.38 (0.05–2.81) | 1.84 (0.61–5.49) | 3.33 (1.22–9.03)a | 1.62 (0.44–5.95) |
8 (maternal 25–35 and paternal 35+) | 224 | 0.83 (0.45–1.54) | 1.09 (0.43–2.76) | 0.94 (0.35–2.50) | 1.13 (0.45–2.85) | 1.04 (0.42–2.58) | 0.82 (0.25–2.67) |
9 (maternal 35+ and paternal 35+) | 163 | 2.13 (1.17–3.91)a | 3.54 (1.54–8.15)a | 1.04 (0.35–3.12) | 2.15 (0.74–6.20) | 3.16 (1.33–7.52)a | 2.93 (1.09–7.85)a |
Singletons | |||||||
1 (maternal <25 and paternal <25) | 633 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
2 (maternal 25–35 and paternal <25) | 357 | 1.16 (0.75–1.80) | 2.39 (1.24–4.58)a | 0.82 (0.38–1.77) | 1.11 (0.54–2.30) | 1.48 (0.74–2.94) | 1.25 (0.60–2.60) |
3 (maternal 35+ and paternal <25) | 79 | 1.33 (0.56–3.15) | 1.48 (0.46–4.73) | 1.24 (0.26–5.92) | 1.79 (0.43–7.47) | 1.09 (0.25–4.87) | 1.60 (0.41–6.27) |
4 (maternal <25 and paternal 25–35) | 1107 | 0.99 (0.69–1.41) | 1.16 (0.66–2.04) | 0.72 (0.40–1.33) | 0.76 (0.41–1.39) | 1.43 (0.80–2.56) | 1.07 (0.57–2.00) |
5 (maternal 25–35 and paternal 25–35) | 933 | 1.00 (0.70–1.42) | 1.23 (0.71–2.16) | 0.69 (0.37–1.27) | 1.14 (0.64–2.03) | 1.57 (0.89–2.75) | 1.30 (0.71–2.37) |
6 (maternal 35+ and paternal 25–35) | 273 | 1.03 (0.62–1.71) | 1.49 (0.67–3.31) | 0.72 (0.28–1.87) | 1.19 (0.52–2.74) | 2.32 (1.13–4.75)a | 1.65 (0.71–3.83) |
7 (maternal <25 and paternal 35+) | 90 | 1.18 (0.51–2.71) | 0.88 (0.20–3.77) | 0.32 (0.03–3.48) | 1.80 (0.57–5.74) | 3.28 (1.15–9.32)a | 1.57 (0.40–6.13) |
8 (maternal 25–35 and paternal 35+) | 162 | 0.80 (0.42–1.52) | 1.08 (0.41–2.83) | 0.93 (0.34–2.59) | 1.15 (0.44–3.01) | 1.00 (0.38–2.65) | 0.79 (0.23–2.75) |
9 (maternal 35+ and paternal 35+) | 124 | 2.06 (1.10–3.86)a | 3.47 (1.46–8.25)a | 0.96 (0.30–3.12) | 2.18 (0.73–6.56) | 3.31 (1.36–8.02)a | 3.00 (1.10–8.20)a |
Models adjusted for maternal age, race, education, insurance, married/living as married, previous live birth, and pregnancy smoking.
P < .05.