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Effects of intracolonic (i.c.) administration of PAR1-activating peptide TFLLR-NH2, control peptide RLLFT-NH2, or their vehicle (saline) on weight (A), macroscopic-damage score (B), and MPO activity (C), in C57BL/6 mice that have received an intracolonic administration of TNBS (1 mg/mouse in 40% ethanol). Values are mean ± SEM; n = 10 per group. *Significantly different from RLLFT-NH2–treated group.
