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. Author manuscript; available in PMC: 2018 Jan 24.
Published in final edited form as: J Am Coll Cardiol. 2017 Jan 24;69(3):291–299. doi: 10.1016/j.jacc.2016.10.059

Table 2.

Relative Hazards of AF with HRV Decrease

Measure Model 1* Model 2 Model 3 Model 4§

HR 95% CI HR 95% CI HR 95% CI HR 95% CI
Mean RR interval 1.01 0.96-1.06 0.96 0.92-1.01 0.91 0.83-1.00 0.91 0.83-1.01
Log (SDNN) 1.18 1.13-1.25 1.10 1.05-1.16 1.14 1.08-1.21 1.12 1.06-1.19
Log (RMSSD) 1.07 1.02-1.13 1.04 0.99-1.10 1.07 1.01-1.14 1.06 1.00-1.12
Log (HF) 1.14 1.09-1.20 1.11 1.06-1.17 1.12 1.06-1.17 1.10 1.05-1.16
Log (LF) 1.24 1.18-1.30 1.16 1.11-1.22 1.17 1.11-1.23 1.16 1.10-1.22
Log (LF/HF) 1.15 1.09-1.21 1.08 1.03-1.14 1.08 1.03-1.14 1.08 1.03-1.14
*

Model 1: adjusted for age, race, and sex.

Model 2: adjusted for adjusted for model 1 covariates, and prevalent CHD, diabetes, hypertension, prevalent heart failure, smoking status, alcohol intake, education level, LDL cholesterol, HDL cholesterol, study center, and BMI.

Model 3: adjusted for model 2 covariates, and heart rate (no change with additional adjustment of Cornell voltage).

§

Model 4: adjusted for model 3 covariates, and incident CHD, and incident heart failure.

Hazard ratios (HR) are expressed per SD lower heart rate variability (HRV) measures.

AF = atrial fibrillation; CI = confidence interval; other abbreviations as in Table 1.