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Bicarbonate-centered and physicochemical approach
| Traditional approach (bicarbonate centered) | Physicochemical (Stewart) approach |
|---|---|
| CO2/HCO3– equilibrium | CO2/HCO3– equilibrium |
| Henderson-Hasselbalch equation | Electroneutrality |
| Anion gap | Strong ion difference |
| “Delta/delta” | Water dissociation |
| Weak acid dissociation |
