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. Author manuscript; available in PMC: 2018 Jan 3.
Published in final edited form as: Anal Chem. 2016 Nov 22;89(1):314–341. doi: 10.1021/acs.analchem.6b04278

Figure 4.

Figure 4

Administering dexamethasone via retrodialysis diminishes the damage caused by probe implantation. (Left) Immunoreactivity for ED-1 in sections containing the tracks of probes without (top) or with dexamethasone (bottom). (Right) Evoked DA responses (mean ± SEM, n = 6 per group) recorded at the outlet of microdialysis probes 5 days after implantation. Without dexamethasone (blue) the stimulus evoked no response. With dexamethasone (red), the stimulus evoked clear and reproducible responses. Adapted with permission from Varner, E. L.; Jaquins-Gerstl, A.; Michael, A. C. ACS Chem. Neurosci. 2016, 7 (6), 728–736 (ref 79). Copyright 2016, American Chemical Society.