PEI-immobilized PSMA/polystyrene microfiber mesh capture and remove exDNA and HMGB1. Human DAMPs generated by sonication-induced cell death were treated with PEI-immobilized PSMA/polystyrene meshes at various surface sizes. The levels of (A) exDNAs, (B) HMGB1, (C) ATP and (D) uric acid in the DAMPs were determined by PicoGreen assay, ELISA, Bioluminescence assay and Fluorometric assay, respectively. Error bars are S.D.. * Significant different (P < 0.05), vs Untreated. ** Significant different (P < 0.01), vs Untreated.