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Compound 20c suppressed the initiation of UPR. (A, B) Respective immunoblots and statistical analysis of the protein levels of p-eIF2α, eIF2α, ATF4, CHOP, XBP1s/XBP1, and ATF6(50)/ATF6. Data are shown as the mean±SEM. n=4–5. One-way ANOVA with Dunnett's test was used for statistical analysis. *P<0.05, **P<0.01 vs the control group. #P<0.05, ##P<0.01 vs the tunicamycin group.
