Skip to main content
. 2016 Oct 3;37(12):1563–1573. doi: 10.1038/aps.2016.97

Figure 3.

Figure 3

Effects of hesperetin on the steady-state activation of Nav1.5 channels expressed in HEK 293 cells. (A) Representative traces showing the steady-state activation of Nav1.5 currents that were triggered by 500-ms pulses causing depolarization (increasing in steps of 5 mV every 1 s) from a holding potential of −120 mV to potentials ranging from −100 to 0 mV in the absence or presence of 100 μmol/L hesperetin. (B) G/Gmax curves representing the steady-state activation of Nav1.5 currents in the absence or presence of 100 μmol/L hesperetin were fitted with the Boltzmann equation (n=8, P<0.05). Data are expressed as the mean±SEM.