Frequency of Mercuri grades in thigh and calf muscles of HSPB1 patients at baseline (n = 8). The y axis represents the percentage of patients with a particular Mercuri score for each muscle. At the level of the thigh there is sparing of Rectus Femoris and Adductor Longus. At the level of the calf the soleus, medial and lateral gastrocnemius and peroneus longus muscles are more severely affected. RF = Rectus Femoris, VL = Vastus Lateralis, VI = Vastus Intermedius, VM = Vastus Medialis, BFLH = Biceps Femoris Long Head, BFSH = Biceps Femoris Short Head, ST = Semitendinosus, SM = Semimembranosus, AL = Adductor Longus, AM = Adductor Magnus, Sa = Sartorius, G = Gracilis, MG = Medial Head of Gastrocnemius, LG = Lateral Head of Gastrocnemius, So = Soleus, TP = Tibialis Posterior, TA = Tibialis Anterior, EHL = Extensor Hallucis Longus, PL = Peroneus Longus.