Table 1.
A summary of the patients included in the study, their mutation, age of onset and country of origin.
| Family | No. affected | Inheritance | Mean age at onset/year | Origin | Mutation |
|---|---|---|---|---|---|
| 1 | 2 | AD | 40 | England | Pro39Leu |
| 2 | 1 | Sporadic | 30 | England | Gly84Arg |
| 3 | 2 | AD | 55 | England | Gly84Arg |
| 4 | 1 | AR | 40 | Pakistan | Leu99Met |
| 5 | 1 | Sporadic | 20 | Somalia | Ser135Tyr |
| 6 | 4 | AD | 20 | Poland | Ser135Phe |
| 7 | 6 | AD | 15 | Canada | Ser135Phe |
| 8 | 2 | AD | 30 | Gujurat | Arg140Gly |
| 9 | 1 | AD | 40 | Gujurat | Arg140Gly |
| 10 | 2 | AD | 30 | Gujurat | Arg140Gly |
| 11 | 2 | AD | 44 | Gujurat | Arg140Gly |
| 12 | 1 | AD | 40 | India | Arg140Gly |
| 13 | 5 | AD | 30 | England | Gln175X |
| 14 | 11 | AD | 13 | Ireland | Pro182Ala |