Figure 8.
A2 deletion prevented I/R injury-induced impairment of inner retina function. (a) Amplitudes of the pSTRs are plotted against stimulus intensity showing impaired function of the inner retinal neurons at 4 weeks after I/R injury. **P<0.01 versus WT sham, $P<0.0001 versus WT sham, #P<0.0001 versus WT I/R. WT sham and WT I/R: n=7, A2−/− sham and A2−/− I/R: n=8. Data are presented as mean±S.E.M. (b) Averaged responses to 5 ms flashes are shown for the two highest intensities in panel a showing improved response of A2−/− I/R at 5 × 10−5 cd.s/m2 (top panel) and significant protection at 10−4 cd.s/m2 (bottom panel).The pSTR amplitude was measured at 110 ms after the flash