Figure 8.

AMPK/PKC signal was essential for adiponectin inhibited apoptosis of adipocytes. (a) Protein levels of p-AMPK and p-PKC of adipocytes infected with pAd-APN or si-APN for 48 h, then incubated with compound C (n=3). (b) Protein levels of PPARα, ATF2, CHOP, Bax, Bcl-2 and cleaved-caspase 3 of adipocytes infected with pAd-APN or si-APN, then incubated with compound C (n=3). (c) Protein levels of p-AMPK and p-PKC of adipocytes infected with pAd-APN or si-APN, then incubated with GF109203X (n=3). (d) Protein levels of PPARα, ATF2, GRP78, cleaved-caspase 9 and cleaved-caspase 3 of adipocytes pre-infected with pAd-APN or si-APN, incubated with GF109203X (n=3); pAd-APN, recombinant adenovirus overexpression vector of adiponectin; si-APN, recombinant lentiviral interference vector of adiponectin. Values are means±S.D. *P<0.05 compared with the control group