Figure 7.
miR-30s reduce the rate of HG-induced MPC5 apoptosis. (a) miR-30 inhibitors significantly increase MPC5 apoptosis (n=3). (b) miR-30 mimics inhibit HG-induced MPC5 apoptosis (n=3). (c) miR-30 inhibitors induce the expression of Bax (n=3) and cleaved caspase 3 (n=4). (d) miR-30 mimics suppress the HG-induced upregulation of Bax and cleaved caspase 3 (n=3). Bars represent mean±S.E.M. *P<0.05, **P<0.01, and ***P<0.001