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Effect of SPOP on tumor growth and tumor death in vivo. (a) Representative bioluminescence imaging and xenografts. (b) Tumor growth curves were indicated by bioluminescence (photons/s). (c) The apoptosis level and Ki-67 expression level of subcutaneous tumors were detected with TUNEL and IHC, respectively. The representative images are from the same tumor samples. *P<0.05. Data represent the results from three independent experiments
