Table 1. Clinical characteristics and SPOP methylation in 118 CRC patients.
| Clinical characteristics | Number(n=118) |
SPOP methylation |
P | |
|---|---|---|---|---|
| Methylated(n=31) | Unmethylated(n=87) | |||
| Age (years) | ||||
| ⩽60 | 45 | 13 | 32 | 0.669 |
| >60 | 73 | 18 | 55 | |
| Gender | ||||
| Male | 67 | 14 | 53 | 0.144 |
| Female | 51 | 17 | 34 | |
| Differentiation | ||||
| Well/moderate | 60 | 13 | 47 | 0.298 |
| Poor | 58 | 18 | 40 | |
| TNM stage | ||||
| Stage I | 26 | 12 | 14 | 0.013* |
| Stage II/III | 92 | 19 | 73 | |
| Lymph node | ||||
| Positive | 53 | 8 | 45 | 0.020* |
| Negative | 65 | 23 | 42 | |
* indicates statistically significant difference