Table 1. Clinical characteristics and SPOP methylation in 118 CRC patients.
Clinical characteristics | Number(n=118) |
SPOP methylation |
P | |
---|---|---|---|---|
Methylated(n=31) | Unmethylated(n=87) | |||
Age (years) | ||||
⩽60 | 45 | 13 | 32 | 0.669 |
>60 | 73 | 18 | 55 | |
Gender | ||||
Male | 67 | 14 | 53 | 0.144 |
Female | 51 | 17 | 34 | |
Differentiation | ||||
Well/moderate | 60 | 13 | 47 | 0.298 |
Poor | 58 | 18 | 40 | |
TNM stage | ||||
Stage I | 26 | 12 | 14 | 0.013* |
Stage II/III | 92 | 19 | 73 | |
Lymph node | ||||
Positive | 53 | 8 | 45 | 0.020* |
Negative | 65 | 23 | 42 |
* indicates statistically significant difference