Table 2. Univariate and multivariate analyses of predictors of overall survival in bladder cancer patients.

Variables	Death				Univariable analysis	Multivariable analysis
	Yes	No	N	%	P-valuea	HR (95% CI)	P-valueb
Age
<69	13	13	26	44.8	0.963
≥69	16	16	32	55.2
Gender
Male	23	26	49	84.5	0.298	4.447 (1.350–14.645)	0.014
Female	6	3	9	15.5
Tumor grade
Low	2	1	3	5.3	0.752
High	27	27	54	94.7
Tumor stage
I–II	9	19	28	50.0	0.002	6.083 (2.141–17.284)	0.001
III–IV	19	9	28	50.0
Lymph node invasion
Yes	6	1	7	16.3	0.005
No	15	21	36	83.7
ERBB3
High	27	19	46	79.3	0.026	4.575 (1.042–20.084)	0.044
Low	2	10	12	20.7
DNMT1
High	15	11	26	44.8	0.432
Low	14	18	32	55.2
miR-148-3p
High	15	17	32	55.2	0.659
Low	14	12	26	44.8

Abbreviations: 95% CI, 95% confidence interval; HR, hazard risk ratio

^aStatistical analysis was conducted by Kaplan–Meier method (log-rank test)

^bCox proportional hazards regression