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. 2016 Dec 1;7(12):e2499. doi: 10.1038/cddis.2016.389

Figure 5.

Figure 5

CA treatment improves AD brain markers in 3xTg AD mice. Quantitative immunohistochemistry of hippocampal sections from 3xTg AD mice treated with CA or vehicle (Control). After CA treatment, 3xTg AD hippocampus displayed increased MAP2/neuropil and synaptophysin/synaptic densities, and reduced GFAP/astrocytosis and p-tau (n=8–9 mice/group; *P<0.05, **P<0.01 by t-test). Scale bar, 40 μm